Aristóteles Núñez, in charge at the time of the government's tax administration, Servicio de Administración Tributaria, said that people involved in the Panama Papers case can still make tax declarations and pay taxes on their investments. Being Mexican and having foreign investments or bank accounts is not a crime, but having income and not declaring it is illegal. If investments are categorized as tax evasion, fines of up to 100% of the omitted tax payment can result, as well as three months to nine years imprisonment.[406]
From 1903 to 1968, Panama was a constitutional democracy dominated by a commercially oriented oligarchy. During the 1950s, the Panamanian military began to challenge the oligarchy's political hegemony. The early 1960s saw also the beginning of sustained pressure in Panama for the renegotiation of the Hay–Bunau-Varilla Treaty, including riots that broke out in early 1964, resulting in widespread looting and dozens of deaths, and the evacuation of the American embassy.[26]
By 1900 Panama wanted to declare itself independent from Colombia and in 1903, Panama declared independence and the U.S. recognized the sovereignty of the new country. Colombia finally relinquished in 1921 and declared Panama a separate nation. As U.S. presence increased with the building of the canal, taken on from the French, but the U.S. influence and intervention was not welcomed in all circles of Panama.

Rami Makhlouf, a maternal cousin of Bashar Al-Assad, was worth an estimated $5 billion before the Syrian Civil War, and had control of 60% of the economy. He was subject to sanctions by the United States and the European Union, and controlled Syria's oil and telecommunications business.[383] The US Treasury charged that Pangates, a company registered to him, supplied the Assad government with a thousand tonnes of aviation fuel.[384] However, the Makhloufs were able to continue to operate via Panama shell companies,[103] registered in the British Virgin Islands, and so not subject to US law – however, on May 9, 2011, the EU issued its own sanctions, and these were extended by an order in council to the British Virgin Islands in July 2011.[385] Mossack Fonseca decided September 6 to resign from Makhlouf's companies. By then, Makhlouf had already cut ties with his bank. HSBC told the law firm that the Swiss authorities had frozen Makhlouf's accounts, and that "they have had no contact with the beneficial owner of this company since the last 3 months".[385]

Businesswoman Ingibjörg Pálmadóttir and her husband Jón Ásgeir Jóhannesson have for several years financed their business dealings through a Panamanian company, Guru Invest, which owns shares in retailer Sports Direct through Rhapsody Investments (Europe), based in Luxembourg.[202] Guru Invest paid around US$16 million to Glitnir bank after it crashed to cover the debt of Gaumur, one of Jón Ásgeir's companies, and loaned ISK 100 million to Jón Ásgeir's company Þú Blásól through an offshore company he owns named Jovita. Asked by journalists at Kjarninn where that money came from, Ingibjörg did not reply.[202] Ingibjörg is the primary owner of the 365 media group, which owns the Icelandic news outlets Ví, television channel Stöð 2 and radio stations Bylgjan, X-ið [is] and FM 957, none of which seem to be reporting this disclosure.[202]